Guide to Mutation Detection

Detection of KatG/inhA Mutation to Guide Isoniazid and Ethionamide Use for Drug-resistant Tuberculosis

BACKGROUND Depending on the presence of mutations that determine isoniazid (INH) susceptibility (katG and inhA), Mycobacterium tuberculosis may be susceptible to high doses of INH or ethionamide (ETH). OBJECTIVE To describe the INH resistance profile and association of katG mutation with previous INH treatment and level of drug resistance based on rapid molecular drug susceptibility testing (...

Guide to Antibody Labeling and Detection

Insensitivity to pain due to Genetic Mutation

Pain is neuroanatomically, psychologically and neurophysiologically complicated and its first function is protecting all alive creature body. This issue is so questionable and interesting that people who don’t feel pain how face this sensation and what problems threaten them. So many researchers by using 73 references, articles from electronical and library references have done a clinical...

Detection of the mutation may guide treatment of heart and muscle in Duchenne muscular dystrophy

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Mutation Detection

Since the original description of Helicobacter plvori by Warren and Marshall in 1983 there has been a virtual explosion in interest in this organism. It is now causally linked to chronic gastritis, peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma and possibly gastric cancer. It has proved to be the single most important advance in modern gastroenterology. This book is a ...